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范长征，女，湖南常德人，工学博士，博士生导师，美国Rice University访问学者(2016-2017年)
主要从事基于功能微生物、基因工程菌的环境污染治理与废物资源化利用的高效新技术与关键理论研究，在生物技术改造微生物修复重金属污染、功能微生物用于木质纤维素废物资源化和重金属污染修复领域取得了一定的创新性成果。
主要研究方向：
（1）固体废物处理与资源化；
（2）基于细胞表面展示技术的基因工程菌构建策略及其在重金属/持久性有机物污染湿地修复中的应用；
（3）重金属/持久性有机物污染环境中修复机理、功能基因的传递机制及高效修复策略。
主持国家自然科学基金2项：1项国家自然科学基金面上项目“基于微生物细胞表面展示技术的湿地重金属污染的特异性吸附转化研究”（No.51679084)，1项国家自然科学基金青年基金项目“基于基因多样性分析的堆肥过程中木质纤维素降解微生物群落结构与功能研究”（No.50908079)。作为主要参与人参与了国家自然科学基金项目10项、科技部国际合作项目1项、国家“863”计划1项、湖南省科技重大专项1项等科研项目研究。
联系方式：湖南大学，环境科学与工程学院，长沙市岳麓区，邮编:410082
E-mail：fancz@hnu.edu.cn; Tel：13787102427
Dr. Changzheng Fan
College of Environmental Science & Engineering,Hunan University,Yuelu District,Chasha,Hunan
代表性论文：
(1)Xiang Tang, Pingfeng Yu, Lin Tang, Man Zhou, Changzheng Fan*, Yue Lu, Jacques Mathieu, Weiping Xiong, Pedro J. Alvarez*. Bacteriophages from Arsenic-Resistant Bacteria Transduced Resistance Genes, which Changed Arsenic Speciation and Increased Soil Toxicity. Environmental Science and Technology Letters. 2019, 6, 675-680.
(2)Changzheng Fan*, Man Zhou, Xiang Tang, Guangming Zeng*, Qiuxiang Xu, Biao Song, Rui Gong, Baowei Zhang, Weiping Xiong, Yue Lu, Haoran Dong, Ning Ding, Zhili Luo, Lingyu Wang, Jiaqi Wei. Triclosan Enhances Short-chain Fatty Acid Production from Sludge Fermentation by Elevating Transcriptional Activity of acidogenesis Bacteria. Chemical Engineering Journal.2020,384, 1-10.
(3) Xiang Tang, Guangming Zeng*, Changzheng Fan*, Man Zhou, Lin Tang, Jingjing Zhu, Jia Wan, Danlian Huang, Ming Chen, Piao Xu, Chen Zhang, Yue Lu, Weiping Xiong. Chromosomal expression of CadR on Pseudomonas aeruginosa for the removal of Cd(II) from aqueous solutions. Science of the Total Environment.2018, 636: 1355–1361.
(4) Lunhui Lu, Guangming Zeng*, Changzheng Fan*, Jinsong Guo, Jiachao Zhang, Ming Chen, Haipeng Wu, Yujie Yuan, Xiaoxiao He, Yan He. Environmental factors shaping the abundance and distribution of laccase-encoding bacterial community with potential phenolic oxidase capacity during composting. Applied Microbiology and Biotechnology. 2015, 99(21): 9191-9201.
(5) Linjing Deng, Guangming Zeng*, Changzheng Fan*, Lunhui Lu, Xunfeng Chen, Ming Chen, Haipeng Wu, Xiaoxiao He, Yan He. Response of rhizosphere microbial community structure and diversity to heavy metal co-pollution in arable soil. Applied Microbiology and Biotechnology. 2015, 99(19): 8259-8269.
(6) Lunhui Lu, Guangming Zeng*, Changzheng Fan*, Jiachao Zhang, Anwei Chen, Ming Chen, Min Jiang, Yujie Yuan, Haipeng Wu, Mingyong Lai, Yibin He. Diversity of Two-Domain Laccase-Like Multicopper Oxidase Genes in Streptomyces spp.: Identification of Genes Potentially Involved in Extracellular Activities and Lignocellulose Degradation during Composting of Agricultural Waste. Applied and Environmental Microbiology. 2014, 80(11): 3305-3314.
(7) Lunhui Lu, Guangming Zeng*, Changzheng Fan*, Xiujuan Ren, Cong Wang, Qianru Zhao, Jiachao Zhang, Ming Chen, Anwei Chen, Min Jiang. Characterization of a laccase-like multicopper oxidase from newly isolated Streptomyces sp. C1 in agricultural waste compost and enzymatic decolorization of azo dyes. Biochemical Engineering Journal. 2013, 72: 70-76.
(8) Xiaofeng Ding, Changzheng Fan, Jianlin Zhou, Yingli Zhong, Rushi Liu, Kaiqun Ren, Xiang Hu, Chang Luo, Shunyong Xiao, Yeqi Wang, Du Feng, Jian Zhang*. GAS41 interacts with transcription factor AP-2β and stimulates AP-2β-mediated transactivation. Nucleic Acids Research. 2006, 34(9): 2570-2578.
(9) Jianlin Zhou #, Changzheng Fan #, Yingli Zhong #, Yunhai Liu, Mingjun Liu, Aidong Zhou, Kaiqun Ren, Jian Zhang*. Genomic organization, promoter characterization and roles of Sp1 and AP-2 in the basal transcription of mouse PDIP1 gene. FEBS Letters, 2005, 579(7): 1715-1722.
(10) 任秀娟, 范长征*, 鲁伦慧, 王聪, 曾光明, 农业废物堆肥中高产漆酶新菌株的分离鉴定及酶学性质研究. 环境科学, 2012, 33(9): 3220-3227.
(11) 范长征*, 王聪, 鲁伦慧, 刘谦, 曾光明. 湘江四环素及抗性基因含量特征及其季节变化. 湖南大学学报(自然科学版), 2015, 42(6): 107-112.
(12) 李凤, 曾光明*, 范长征, 李贞, 肖勇. 农业有机废物与城市生活垃圾堆肥高温期微生物种群结构比较. 微生物学通报, 2009, 36(11): 1657-1663.
授权专利：
(1) 【发明人】：范长征，曾光明，杨春平，梁婕，杨朝晖，李凤，李贞，肖勇。【专利名称】：堆肥中生物酶基因多样性的分析方法。【申请日】：2009年05月14日。【专利号】：ZL 200910043399.0。
(2) 【发明人】：曾光明，范长征，杨春平，汤琳，李贞，李凤，肖勇。【专利名称】：堆肥微生物总DNA的提取与纯化方法。【申请日】：2009年05月14日。【专利号】：ZL 200910043400.X。
本课题组目前还可招收1名博士研究生和多名硕士研究生，欢迎有兴趣的同学报考本课题组硕士和博士研究生！
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